2015年8月14日金曜日

The oxidative stress reduction effect of coffee

In women, clinical research had been reported showing oxidative stress-reducing action by ingestion of coffee. (Wien Klin Wochenschr. 2015 Mar 19.) In the past a lot of research, Coffee and green tea, health maintenance and lifestyle-related disease prevention effect by ingestion of black tea has been shown. One polyphenol contained in coffee, antioxidant effect of chlorogenic acid, It is believed that effect through the action, such as green tea catechin. In this study, Intake and coffee, associated with oxidative stress has been verified. In particular, Women 415 people (the 49-year-old average age) to the subject, Questionnaire on coffee intake is carried out, Blood oxidative stress metabolites (d-ROMs) has been measured. As a result of the analysis, In the women who consume three or more cups of coffee per day, Compared from 0 cups to 2 cups of intake group, Oxidative stress metabolites were significantly lower. (336 ± 67 vs. 358 ± 80 Carr U; p <0.05) The results of multivariate analysis, Intake and of coffee, Significant association with the reduction of oxidative stress metabolites were observed. (P <0.05) From the above data, -Related intake of coffee oxide and stress reduction in women is suggested. In DHC, we have a variety of tea, herbal tea, coffee, decaffeinated beverages and commercialized. By previous epidemiological studies, reduction of lifestyle-related diseases risk by ingestion of coffee has been known. For example, ingestion of type 2 diabetes risk reduction due to coffee, reduced risk of stroke, lowering depression risk, decrease in liver cancer risk, and suppressing reduction of cognitive function. The coffee contains a chlorogenic acid is one of phytochemicals, lifestyle diseases preventive effect via anti-oxidative effects has been suggested. (As a major component other than caffeine in coffee, ferulic acid (ferulic acid), caffeic acid (caffeic acid,), chlorogenic acid (chlorogenic acid) are known, it indicates any antioxidant effect. Of these chlorogenic acid is relatively abundant in the middle.) This epidemiological studies and clinical trials of up to, improvement of hypertension, reduction of cardiovascular disease (atherosclerotic disease) risk, such as an anti-cancer effect has been reported. For example, research such as the following have been known. Total mortality and cardiovascular disease risk reduction effect of coffee consumption: meta-analysis Relationship between the intake and urinary cancer of coffee @ meta-analysis The prostate cancer risk reduction effect of the intake of coffee @ meta-analysis And liver cancer risk reduction effect of coffee Association between intake and prostate cancer risk of coffee The oropharyngeal cancer risk reduction effect of the intake of coffee Relationship of chocolate and coffee intake and liver function @ HIV-HCV co-infected persons Intake of coffee to suppress depression risk women

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